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SnapKin: a snapshot deep learning ensemble for kinase-substrate prediction from phosphoproteomics data

A major challenge in mass spectrometry-based phosphoproteomics lies in identifying the substrates of kinases, as currently only a small fraction of substrates identified can be confidently linked with a known kinase. Machine learning techniques are promising approaches for leveraging large-scale pho...

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Detalles Bibliográficos
Autores principales: Xiao, Di, Lin, Michael, Liu, Chunlei, Geddes, Thomas A, Burchfield, James G, Parker, Benjamin L, Humphrey, Sean J, Yang, Pengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632189/
https://www.ncbi.nlm.nih.gov/pubmed/37954574
http://dx.doi.org/10.1093/nargab/lqad099