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Complement factor H Y402H polymorphism results in diminishing CD4(+) T cells and increasing C-reactive protein in plasma

Age-related macular degeneration (AMD) is a common cause of visual loss among the elderly. Genetic variants in the gene encoding complement factor H (CFH) have been identified as an AMD susceptibility gene, however, the mechanistic link is debated. Here, we investigated the link between the CFH Y402...

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Detalles Bibliográficos
Autores principales: Nielsen, Marie Krogh, Subhi, Yousif, Falk, Mads, Singh, Amardeep, Sørensen, Torben Lykke, Nissen, Mogens Holst, Faber, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632322/
https://www.ncbi.nlm.nih.gov/pubmed/37940659
http://dx.doi.org/10.1038/s41598-023-46827-0