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Nde1 promotes Lis1-mediated activation of dynein

Cytoplasmic dynein drives the motility and force generation functions towards the microtubule minus end. The assembly of dynein with dynactin and a cargo adaptor in an active transport complex is facilitated by Lis1 and Nde1/Ndel1. Recent studies proposed that Lis1 relieves dynein from its autoinhib...

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Detalles Bibliográficos
Autores principales: Zhao, Yuanchang, Oten, Sena, Yildiz, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632352/
https://www.ncbi.nlm.nih.gov/pubmed/37940657
http://dx.doi.org/10.1038/s41467-023-42907-x