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Neural circuit selective for fast but not slow dopamine increases in drug reward

The faster a drug enters the brain, the greater its addictive potential, yet the brain circuits underlying the rate dependency to drug reward remain unresolved. With simultaneous PET-fMRI we linked dynamics of dopamine signaling, brain activity/connectivity, and self-reported ‘high’ in 20 adults rec...

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Detalles Bibliográficos
Autores principales: Manza, Peter, Tomasi, Dardo, Shokri-Kojori, Ehsan, Zhang, Rui, Kroll, Danielle, Feldman, Dana, McPherson, Katherine, Biesecker, Catherine, Dennis, Evan, Johnson, Allison, Yuan, Kai, Wang, Wen-Tung, Yonga, Michele-Vera, Wang, Gene-Jack, Volkow, Nora D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632365/
https://www.ncbi.nlm.nih.gov/pubmed/37938560
http://dx.doi.org/10.1038/s41467-023-41972-6