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Ficolin-2 amplifies inflammation in macrophage-smooth muscle cell cross-talk and increases monocyte transmigration by mechanisms involving IL-1β and IL-6

Ficolin-2, recently identified in atherosclerotic plaques, has been correlated with future acute cardiovascular events, but its role remains unknown. We hypothesize that it could influence plaque vulnerability by interfering in the cross-talk between macrophages (MØ) and smooth muscle cells (SMC). T...

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Detalles Bibliográficos
Autores principales: Macarie, Răzvan Daniel, Tucureanu, Monica Mădălina, Ciortan, Letiția, Gan, Ana-Maria, Butoi, Elena, Mânduțeanu, Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632380/
https://www.ncbi.nlm.nih.gov/pubmed/37940674
http://dx.doi.org/10.1038/s41598-023-46770-0