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Opto-SICM framework combines optogenetics with scanning ion conductance microscopy for probing cell-to-cell contacts

We present a novel framework, Opto-SICM, for studies of cellular interactions in live cells with high spatiotemporal resolution. The approach combines scanning ion conductance microscopy, SICM, and cell-type-specific optogenetic interrogation. Light-excitable cardiac fibroblasts (FB) and myofibrobla...

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Detalles Bibliográficos
Autores principales: Song, Qianqian, Alvarez-Laviada, Anita, Schrup, Sarah E., Reilly-O’Donnell, Benedict, Entcheva, Emilia, Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632396/
https://www.ncbi.nlm.nih.gov/pubmed/37938652
http://dx.doi.org/10.1038/s42003-023-05509-3