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Determining zebrafish dorsal organizer size by a negative feedback loop between canonical/non-canonical Wnts and Tlr4/NFκB

In vertebrate embryos, the canonical Wnt ligand primes the formation of dorsal organizers that govern dorsal-ventral patterns by secreting BMP antagonists. In contrast, in Drosophila embryos, Toll-like receptor (Tlr)-mediated NFκB activation initiates dorsal-ventral patterning, wherein Wnt-mediated...

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Detalles Bibliográficos
Autores principales: Zou, Juqi, Anai, Satoshi, Ota, Satoshi, Ishitani, Shizuka, Oginuma, Masayuki, Ishitani, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632484/
https://www.ncbi.nlm.nih.gov/pubmed/37938219
http://dx.doi.org/10.1038/s41467-023-42963-3