Cargando…

Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease

Sickle cell disease (SCD) is a hereditary hematological disease with high morbidity and mortality rates worldwide. Despite being monogenic, SCD patients display a plethora of disease-associated complications including anemia, oxidative stress, sterile inflammation, vaso-occlusive crisis-related pain...

Descripción completa

Detalles Bibliográficos
Autores principales: Chowdhury, Fabliha A., Colussi, Nicole, Sharma, Malini, Wood, Katherine C., Xu, Julia Z., Freeman, Bruce A., Schopfer, Francisco J., Straub, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632539/
https://www.ncbi.nlm.nih.gov/pubmed/37907055
http://dx.doi.org/10.1016/j.redox.2023.102941