Cargando…
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease
Sickle cell disease (SCD) is a hereditary hematological disease with high morbidity and mortality rates worldwide. Despite being monogenic, SCD patients display a plethora of disease-associated complications including anemia, oxidative stress, sterile inflammation, vaso-occlusive crisis-related pain...
Autores principales: | Chowdhury, Fabliha A., Colussi, Nicole, Sharma, Malini, Wood, Katherine C., Xu, Julia Z., Freeman, Bruce A., Schopfer, Francisco J., Straub, Adam C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632539/ https://www.ncbi.nlm.nih.gov/pubmed/37907055 http://dx.doi.org/10.1016/j.redox.2023.102941 |
Ejemplares similares
-
Olives and Olive Oil Are Sources of Electrophilic Fatty Acid Nitroalkenes
por: Fazzari, Marco, et al.
Publicado: (2014) -
Electrophilic fatty acid nitroalkenes regulate Nrf2 and NF-κB signaling:A medicinal chemistry investigation of structure-function relationships
por: Khoo, Nicholas K. H., et al.
Publicado: (2018) -
Fatty acid nitroalkene reversal of established lung fibrosis
por: Koudelka, Adolf, et al.
Publicado: (2021) -
Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes
por: Grippo, Valentina, et al.
Publicado: (2020) -
Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO(2)) and nitroalkene (RNO(2)) substituents
por: Fazzari, Marco, et al.
Publicado: (2021)