Masking the transmembrane region of the amyloid β precursor protein as a safe means to lower amyloid β production

INTRODUCTION: Reducing brain levels of both soluble and insoluble forms of amyloid beta (Aβ) remains the primary goal of most therapies that target Alzheimer's disease (AD). However, no treatment has so far resulted in patient benefit, and clinical trials of the most promising drug candidates h...

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Detalles Bibliográficos
Autores principales: Khan, Ayesha, Killick, Richard, Wirth, Daniel, Hoogland, Dominique, Hristova, Kalina, Ulmschneider, Jakob P., King, Christopher R., Ulmschneider, Martin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632552/
https://www.ncbi.nlm.nih.gov/pubmed/37954165
http://dx.doi.org/10.1002/trc2.12428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632552/
https://www.ncbi.nlm.nih.gov/pubmed/37954165
http://dx.doi.org/10.1002/trc2.12428

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