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Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice

BACKGROUND: COPD is an incurable disease and a leading cause of death worldwide. In mice, fibroblast growth factor (FGF)10 is essential for lung morphogenesis, and in humans, polymorphisms in the human FGF10 gene correlate with an increased susceptibility to develop COPD. METHODS: We analysed FGF10...

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Detalles Bibliográficos
Autores principales: Hadzic, Stefan, Wu, Cheng-Yu, Gredic, Marija, Pak, Oleg, Loku, Edma, Kraut, Simone, Kojonazarov, Baktybek, Wilhelm, Jochen, Brosien, Monika, Bednorz, Mariola, Seimetz, Michael, Günther, Andreas, Kosanovic, Djuro, Sommer, Natascha, Warburton, David, Li, Xiaokun, Grimminger, Friedrich, Ghofrani, Hossein A., Schermuly, Ralph T., Seeger, Werner, El Agha, Elie, Bellusci, Saverio, Weissmann, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632559/
https://www.ncbi.nlm.nih.gov/pubmed/37884305
http://dx.doi.org/10.1183/13993003.01606-2022