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Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice
BACKGROUND: COPD is an incurable disease and a leading cause of death worldwide. In mice, fibroblast growth factor (FGF)10 is essential for lung morphogenesis, and in humans, polymorphisms in the human FGF10 gene correlate with an increased susceptibility to develop COPD. METHODS: We analysed FGF10...
Autores principales: | Hadzic, Stefan, Wu, Cheng-Yu, Gredic, Marija, Pak, Oleg, Loku, Edma, Kraut, Simone, Kojonazarov, Baktybek, Wilhelm, Jochen, Brosien, Monika, Bednorz, Mariola, Seimetz, Michael, Günther, Andreas, Kosanovic, Djuro, Sommer, Natascha, Warburton, David, Li, Xiaokun, Grimminger, Friedrich, Ghofrani, Hossein A., Schermuly, Ralph T., Seeger, Werner, El Agha, Elie, Bellusci, Saverio, Weissmann, Norbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632559/ https://www.ncbi.nlm.nih.gov/pubmed/37884305 http://dx.doi.org/10.1183/13993003.01606-2022 |
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