The chromatin remodeling factors EP300 and TRRAP are novel SMYD3 interactors involved in the emerging ‘nonmutational epigenetic reprogramming’ cancer hallmark

SMDY3 is a histone-lysine N-methyltransferase involved in several oncogenic processes and is believed to play a major role in various cancer hallmarks. Recently, we identified ATM, BRCA2, CHK2, MTOR, BLM, MET, AMPK, and p130 as direct SMYD3 interactors by taking advantage of a library of rare tripep...

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Detalles Bibliográficos
Autores principales: Fasano, Candida, Lepore Signorile, Martina, Di Nicola, Elisabetta, Pantaleo, Antonino, Forte, Giovanna, De Marco, Katia, Sanese, Paola, Disciglio, Vittoria, Grossi, Valentina, Simone, Cristiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632561/
https://www.ncbi.nlm.nih.gov/pubmed/37954147
http://dx.doi.org/10.1016/j.csbj.2023.10.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632561/
https://www.ncbi.nlm.nih.gov/pubmed/37954147
http://dx.doi.org/10.1016/j.csbj.2023.10.015

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