T-cell dysfunction by pseudohypoxia and autocrine purinergic signaling in chronic lymphocytic leukemia

Acquired T-cell dysfunction is common in chronic B-cell malignancies. Given the strong connection between T-cell metabolism and function, we investigated metabolic alterations as the basis of T-cell dysfunction induced by malignant cells. Using B-cell malignant cell lines and human peripheral blood...

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Detalles Bibliográficos
Autores principales: Montironi, Chiara, Jacobs, Chaja F., Cretenet, Gaspard, Peters, Fleur S., Schomakers, Bauke V., van Weeghel, Michel, Kater, Arnon P., Simon-Molas, Helga, Eldering, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632609/
https://www.ncbi.nlm.nih.gov/pubmed/37552122
http://dx.doi.org/10.1182/bloodadvances.2023010305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632609/
https://www.ncbi.nlm.nih.gov/pubmed/37552122
http://dx.doi.org/10.1182/bloodadvances.2023010305

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