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Modeling unveils sex differences of signaling networks in mouse embryonic stem cells

For a short period during early development of mammalian embryos, both X chromosomes in females are active, before dosage compensation is ensured through X‐chromosome inactivation. In female mouse embryonic stem cells (mESCs), which carry two active X chromosomes, increased X‐dosage affects cell sig...

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Detalles Bibliográficos
Autores principales: Sultana, Zeba, Dorel, Mathurin, Klinger, Bertram, Sieber, Anja, Dunkel, Ilona, Blüthgen, Nils, Schulz, Edda G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632733/
https://www.ncbi.nlm.nih.gov/pubmed/37735975
http://dx.doi.org/10.15252/msb.202211510