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Identification and validation of a novel signature based on T cell marker genes to predict prognosis, immunotherapy response and chemotherapy sensitivity in head and neck squamous carcinoma by integrated analysis of single-cell and bulk RNA-sequencing

T cells are among the most potent anti-tumor cells that are found in humans. Our study sought to develop a reliable signature incorporating T cell marker genes (TMGs) for predicting the prognosis and therapy responsiveness of head and neck squamous cell carcinoma (HNSCC) patients. We downloaded scRN...

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Detalles Bibliográficos
Autores principales: Zhou, Chongchang, Deng, Hongxia, Fang, Yi, Wei, Zhengyu, Shen, Yiming, Qiu, Shijie, Ye, Dong, Shen, Zhisen, Shen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632748/
https://www.ncbi.nlm.nih.gov/pubmed/37954266
http://dx.doi.org/10.1016/j.heliyon.2023.e21381