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CD138 promotes the accumulation and activation of autoreactive T cells in autoimmune MRL/lpr mice

Autoreactive T cells, specifically CD138(+) (syndecan-1) T cells produced in Fas-deficient systemic lupus erythematosus (SLE) mouse models, were shown to significantly promote the generation of autoantibodies. In the present study, Murphy Roths Large lymphoproliferative (MRL/lpr) lupus mice were use...

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Detalles Bibliográficos
Autores principales: Xie, Tianhong, Liu, Xin, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632966/
https://www.ncbi.nlm.nih.gov/pubmed/37954119
http://dx.doi.org/10.3892/etm.2023.12267