Control of A/D type CpG-ODN aggregates to a suitable size for induction of strong immunostimulant activity

Among several types of CpG-ODNs, A/D-type CpG-ODNs have potent adjuvant activity to induce Th-1 immune responses, but exhibit a propensity to aggregate. For the clinical application of A/D-type CpG-ODNs, it is necessary to control such aggregation and obtain a comprehensive understanding of the rela...

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Detalles Bibliográficos
Autores principales: Matsuda, Miyu, Mochizuki, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633530/
https://www.ncbi.nlm.nih.gov/pubmed/37954170
http://dx.doi.org/10.1016/j.bbrep.2023.101573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633530/
https://www.ncbi.nlm.nih.gov/pubmed/37954170
http://dx.doi.org/10.1016/j.bbrep.2023.101573

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