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Control of A/D type CpG-ODN aggregates to a suitable size for induction of strong immunostimulant activity
Among several types of CpG-ODNs, A/D-type CpG-ODNs have potent adjuvant activity to induce Th-1 immune responses, but exhibit a propensity to aggregate. For the clinical application of A/D-type CpG-ODNs, it is necessary to control such aggregation and obtain a comprehensive understanding of the rela...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633530/ https://www.ncbi.nlm.nih.gov/pubmed/37954170 http://dx.doi.org/10.1016/j.bbrep.2023.101573 |