Cargando…

Mobile Affinity Selection Chromatography Analysis of Therapeutic Monoclonal Antibodies

[Image: see text] Federal regulatory agencies require continuous verification of recombinant therapeutic monoclonal antibody (mAb) quality that is commonly achieved in a two-step process. First, the host-cell proteome and metabolome are removed from the production medium by protein A affinity chroma...

Descripción completa

Detalles Bibliográficos
Autores principales: Narsimhan, Meena L., Kim, Jinhee, Morris, Nathan A., Bower, Mary A., Gunawardena, Harsha P., Bowen, Eric, Regnier, Fred E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633814/
https://www.ncbi.nlm.nih.gov/pubmed/37883730
http://dx.doi.org/10.1021/acs.analchem.3c02180