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Dexmedetomidine attenuates the neuroinflammation and cognitive dysfunction in aged mice by targeting the SNHG14/miR‑340/NF‑κB axis

Neuroinflammation plays a key role in the pathogenesis of postoperative cognitive dysfunction (POCD). Results of our previous study demonstrated that dexmedetomidine (Dex) attenuates neuroinflammation in BV2 cells treated with lipopolysaccharide (LPS) by targeting the microRNA (miR)-340/NF-κB axis....

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Detalles Bibliográficos
Autores principales: He, Guangbao, Ni, Hongwei, Wang, Kai, Gao, Hongmei, Li, Yu, Gu, Jiaqiu, Ni, Xin, Wang, Zhiming, Bao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633816/
https://www.ncbi.nlm.nih.gov/pubmed/37954634
http://dx.doi.org/10.3892/br.2023.1682