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Novel 2-substituted-quinoxaline analogs with potential antiproliferative activity against breast cancer: insights into cell cycle arrest, topoisomerase II, and EGFR activity

Breast cancer is a global health concern, with increasing disease burden and disparities in access to healthcare. Late diagnosis and limited treatment options in underserved areas contribute to poor outcomes. In response to this challenge, we developed a novel family of 2-substituted-quinoxaline ana...

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Detalles Bibliográficos
Autores principales: Salem, Manar G., Abu El-ata, Sara A., Elsayed, Elsherbiny H., Mali, Suraj N., Alshwyeh, Hussah Abdullah, Almaimani, Ghassan, Almaimani, Riyad A., Almasmoum, Hussain A., Altwaijry, Najla, Al-Olayan, Ebtesam, Saied, Essa M., Youssef, Mohamed F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633821/
https://www.ncbi.nlm.nih.gov/pubmed/37954422
http://dx.doi.org/10.1039/d3ra06189b