Cargando…
Novel 2-substituted-quinoxaline analogs with potential antiproliferative activity against breast cancer: insights into cell cycle arrest, topoisomerase II, and EGFR activity
Breast cancer is a global health concern, with increasing disease burden and disparities in access to healthcare. Late diagnosis and limited treatment options in underserved areas contribute to poor outcomes. In response to this challenge, we developed a novel family of 2-substituted-quinoxaline ana...
Autores principales: | Salem, Manar G., Abu El-ata, Sara A., Elsayed, Elsherbiny H., Mali, Suraj N., Alshwyeh, Hussah Abdullah, Almaimani, Ghassan, Almaimani, Riyad A., Almasmoum, Hussain A., Altwaijry, Najla, Al-Olayan, Ebtesam, Saied, Essa M., Youssef, Mohamed F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633821/ https://www.ncbi.nlm.nih.gov/pubmed/37954422 http://dx.doi.org/10.1039/d3ra06189b |
Ejemplares similares
-
Unveiling the antitumor potential of novel N-(substituted-phenyl)-8-methoxycoumarin-3-carboxamides as dual inhibitors of VEGFR2 kinase and cytochrome P450 for targeted treatment of hepatocellular carcinoma
por: Radwan, Eman M., et al.
Publicado: (2023) -
Novel 8-Methoxycoumarin-3-Carboxamides with potent anticancer activity against liver cancer via targeting caspase-3/7 and β-tubulin polymerization
por: Alzamami, Ahmad, et al.
Publicado: (2023) -
Solanum Procumbens-Derived Zinc Oxide Nanoparticles Suppress Lung Cancer In Vitro through Elevation of ROS
por: Ibrahim Abdel Aziz, Ibrahim, et al.
Publicado: (2022) -
Potential Predictors of Poor Prognosis among Severe COVID-19 Patients: A Single-Center Study
por: Ghaith, Mazen M., et al.
Publicado: (2021) -
Determinants of breast cancer in Saudi women from Makkah region: a case-control study (breast cancer risk factors among Saudi women)
por: Alsolami, Fatmah J., et al.
Publicado: (2019)