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Syntheses of Minutuminolate and Related Coumarin Natural Products and Evaluation of Their TNF-α Inhibitory Activities

[Image: see text] The concise syntheses of the coumarin natural product, minutuminolate (1), and its related natural products, 7-methoxy-8-(2-acetoxy-3-methyl-1-oxobut-2-enyl) coumarin (2) and muralatin I (3), were accomplished for the first time in 4–5 steps from the commercially available umbellif...

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Detalles Bibliográficos
Autores principales: Choo, Malcolm Zheng Yuan, Khaw, Lachelle Wei Ting, Chai, Christina Li Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633832/
https://www.ncbi.nlm.nih.gov/pubmed/37970054
http://dx.doi.org/10.1021/acsomega.3c06361