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Peptide-based approaches to directly target alpha-synuclein in Parkinson’s disease
Peptides and their mimetics are increasingly recognised as drug-like molecules, particularly for intracellular protein-protein interactions too large for inhibition by small molecules, and inaccessible to larger biologics. In the past two decades, evidence associating the misfolding and aggregation...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633918/ https://www.ncbi.nlm.nih.gov/pubmed/37940962 http://dx.doi.org/10.1186/s13024-023-00675-8 |