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Peptide-based approaches to directly target alpha-synuclein in Parkinson’s disease

Peptides and their mimetics are increasingly recognised as drug-like molecules, particularly for intracellular protein-protein interactions too large for inhibition by small molecules, and inaccessible to larger biologics. In the past two decades, evidence associating the misfolding and aggregation...

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Detalles Bibliográficos
Autores principales: Allen, Scott G., Meade, Richard M., White Stenner, Lucy L., Mason, Jody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633918/
https://www.ncbi.nlm.nih.gov/pubmed/37940962
http://dx.doi.org/10.1186/s13024-023-00675-8