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Exosomal circCOL1A1 promotes angiogenesis via recruiting EIF4A3 protein and activating Smad2/3 pathway in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is the third frequently diagnosed cancer with high incidence and mortality rate worldwide. Our previous report has demonstrated that circCOL1A1 (hsa_circ_0044556) functions as an oncogene in CRC, and Gene Ontology (GO) analysis has also revealed the strong associa...

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Detalles Bibliográficos
Autores principales: Hu, Gui, Lin, Changwei, Gao, Kai, Chen, Miao, Long, Fei, Tian, Buning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633966/
https://www.ncbi.nlm.nih.gov/pubmed/37940881
http://dx.doi.org/10.1186/s10020-023-00747-x