Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells

Deubiquitinases (DUBs) play important roles in various human cancers and targeting DUBs is considered as a novel anticancer therapeutic strategy. Overexpression of ubiquitin specific protease 7 and 22 (USP7 and USP22) are associated with malignancy, therapy resistance, and poor prognosis in many can...

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Detalles Bibliográficos
Autores principales: Zhang, Keqiang, Sun, Ting, Li, Wendong, Guo, Yuming, Li, Aimin, Hsieh, Marcus, Wang, Jinghan, Wu, Jun, Arvanitis, Leonidas, Raz, Dan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634000/
https://www.ncbi.nlm.nih.gov/pubmed/37946202
http://dx.doi.org/10.1186/s12964-023-01320-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634000/
https://www.ncbi.nlm.nih.gov/pubmed/37946202
http://dx.doi.org/10.1186/s12964-023-01320-z

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