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Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells

Deubiquitinases (DUBs) play important roles in various human cancers and targeting DUBs is considered as a novel anticancer therapeutic strategy. Overexpression of ubiquitin specific protease 7 and 22 (USP7 and USP22) are associated with malignancy, therapy resistance, and poor prognosis in many can...

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Detalles Bibliográficos
Autores principales:	Zhang, Keqiang, Sun, Ting, Li, Wendong, Guo, Yuming, Li, Aimin, Hsieh, Marcus, Wang, Jinghan, Wu, Jun, Arvanitis, Leonidas, Raz, Dan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634000/ https://www.ncbi.nlm.nih.gov/pubmed/37946202 http://dx.doi.org/10.1186/s12964-023-01320-z

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