IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A

The unfolded protein response is a survival signaling pathway that is induced during various types of ER stress. Here, we determine IRE1’s role in miRNA regulation during ER stress. During induction of ER stress in human bronchial epithelial cells, we utilized next generation sequencing to demonstra...

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Detalles Bibliográficos
Autores principales: Gebert, Magdalena, Bartoszewska, Sylwia, Opalinski, Lukasz, Collawn, James F., Bartoszewski, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634081/
https://www.ncbi.nlm.nih.gov/pubmed/37946177
http://dx.doi.org/10.1186/s12964-023-01349-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634081/
https://www.ncbi.nlm.nih.gov/pubmed/37946177
http://dx.doi.org/10.1186/s12964-023-01349-0

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