Tacrolimus reverses pemphigus vulgaris serum-induced depletion of desmoglein in HaCaT cells via inhibition of heat shock protein 27 phosphorylation

BACKGROUND: Glucocorticoids are the first-line treatment for Pemphigus vulgaris (PV), but its serious side effects can be life-threatening for PV patients. Tacrolimus (FK506) has been reported to have an adjuvant treatment effect against PV. However, the mechanism underlying the inhibitory effect of...

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Detalles Bibliográficos
Autores principales: Xie, Zhimin, Dai, Xiangnong, Li, Qingqing, Lin, Sifan, Ye, Xingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634089/
https://www.ncbi.nlm.nih.gov/pubmed/37940861
http://dx.doi.org/10.1186/s12865-023-00582-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634089/
https://www.ncbi.nlm.nih.gov/pubmed/37940861
http://dx.doi.org/10.1186/s12865-023-00582-z

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