Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders

DNA sensing is a pivotal component of the innate immune system that is responsible for detecting mislocalized DNA and triggering downstream inflammatory pathways. Among the DNA sensors, cyclic GMP-AMP synthase (cGAS) is a primary player in detecting cytosolic DNA, including foreign DNA from pathogen...

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Detalles Bibliográficos
Autores principales: Huang, Yige, Liu, Bangyan, Sinha, Subhash C., Amin, Sadaf, Gan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634099/
https://www.ncbi.nlm.nih.gov/pubmed/37941028
http://dx.doi.org/10.1186/s13024-023-00672-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634099/
https://www.ncbi.nlm.nih.gov/pubmed/37941028
http://dx.doi.org/10.1186/s13024-023-00672-x

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