Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/β-catenin pathway

BACKGROUND: The aggressive phenotype of fibroblast-like synoviocytes (FLS) has been identified as a contributing factor to the exacerbation of rheumatoid arthritis (RA) through the promotion of synovitis and cartilage damage. Regrettably, there is currently no effective therapeutic intervention avai...

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Detalles Bibliográficos
Autores principales: Guo, Dong, Pan, Haoyan, Lu, Xueying, Chen, Zhong, Zhou, Laixi, Chen, Shuxin, Huang, Jin, Liang, Xinzhi, Xiao, Zhisheng, Zeng, Hua, Shao, Yan, Qi, Weizhong, Xie, Denghui, Lin, Chuangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634117/
https://www.ncbi.nlm.nih.gov/pubmed/37946278
http://dx.doi.org/10.1186/s13075-023-03198-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634117/
https://www.ncbi.nlm.nih.gov/pubmed/37946278
http://dx.doi.org/10.1186/s13075-023-03198-1

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