Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

This study investigated chronic and repeated sleep deprivation (RSD)-induced neuronal changes in hexosamine biosynthetic pathway/O-linked N-acetylglucosamine (HBP/O-GlcNAc) cycling of glucose metabolism and further explored the role of altered O-GlcNAc cycling in promoting neurodegeneration using an...

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Detalles Bibliográficos
Autores principales: Park, Jiwon, Kim, Dong Yeol, Hwang, Geum-Sook, Han, Inn-Oc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634120/
https://www.ncbi.nlm.nih.gov/pubmed/37946213
http://dx.doi.org/10.1186/s12974-023-02944-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634120/
https://www.ncbi.nlm.nih.gov/pubmed/37946213
http://dx.doi.org/10.1186/s12974-023-02944-1

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