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Prognostic impact of severe neutropenia in colorectal cancer patients treated with TAS-102 and bevacizumab, addressing immortal-time bias

BACKGROUND: Several studies have reported an association between severe neutropenia and long-term survival in patients treated with trifluridine-tipiracil (TAS-102). Because some of these studies failed to address immortality time bias, however, their findings should be interpreted with caution. Add...

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Detalles Bibliográficos
Autores principales: Watanabe, Daichi, Fujii, Hironori, Ohata, Koichi, Iihara, Hirotoshi, Makiyama, Akitaka, Kobayashi, Ryo, Hirose, Chiemi, Hishida, Shiori, Matsuoka, Serika, Tajima, Jesse Yu, Kiyama, Shigeru, Takahashi, Takao, Suzuki, Akio, Matsuhashi, Nobuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634158/
https://www.ncbi.nlm.nih.gov/pubmed/37940878
http://dx.doi.org/10.1186/s12885-023-11618-3