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Construction of miRNA-mRNA regulatory network indicates potential biomarkers for primary open-angle glaucoma

BACKGROUND: Trabecular meshwork (TM) dysfunction-induced elevation of intraocular pressure has been identified as the main risk factor of irreversible optic nerve injury in Primary open‑angle glaucoma (POAG). Increasing evidences suggest that microRNA (miRNA) plays a vital role in the pathogenesis o...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoyu, Zhang, Feng, Zhang, Xinyue, Zhou, Dengming, Zhao, Yang, Chen, Baihua, Duan, Xuanchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634160/
https://www.ncbi.nlm.nih.gov/pubmed/37940950
http://dx.doi.org/10.1186/s12920-023-01698-2