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Antitumor effect of toosendanin on oral squamous cell carcinoma via suppression of p-STAT3

BACKGROUND: Toosendanin (TSN) exhibits potent antitumor activity against various tumor cell lines. However, its efficacy against oral squamous cell carcinoma (OSCC) remains unknown. Here, we investigated the effects of TSN on OSCC cells in vitro and verified them in vivo using a patient-derived xeno...

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Detalles Bibliográficos
Autores principales: Wu, Ye, Chen, Lingling, Feng, Cheng, Wang, Tao, He, Shaohai, Zheng, Dali, Lin, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634166/
https://www.ncbi.nlm.nih.gov/pubmed/37946196
http://dx.doi.org/10.1186/s12903-023-03602-x