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INHBA gene silencing inhibits proliferation, migration, and invasion of osteosarcoma cells by repressing TGF-β signaling pathway activation

BACKGROUND: Osteosarcoma (OS) is a refractory malignancy. This study aimed to explore the roles and mechanisms of Inhibin subunit beta A (INHBA) in OS. METHODS: INHBA expression levels in OS tissues and cells were assessed using RT-qPCR and western blotting. The impact of INHBA silencing on OS devel...

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Detalles Bibliográficos
Autores principales: Zhang, Hongyu, Huang, Yuemei, Wen, Qiuting, Li, Yan, Guo, Lin, Ge, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634167/
https://www.ncbi.nlm.nih.gov/pubmed/37940978
http://dx.doi.org/10.1186/s13018-023-04330-2