Lack of HCAR1, the lactate GPCR, signaling promotes autistic-like behavior

The GPCR HCAR1 is known to be the sole receptor for lactate, which modulates its metabolic effects. Despite its significant role in many processes, mice deficient in HCAR1 exhibit no visible phenotype and are healthy and fertile. We performed transcriptomic analysis on HCAR1 deficient cells, in comb...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohammad Nezhady, Mohammad Ali, Cagnone, Gael, Joyal, Jean-Sébastien, Chemtob, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634184/
https://www.ncbi.nlm.nih.gov/pubmed/37940970
http://dx.doi.org/10.1186/s12964-023-01188-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634184/
https://www.ncbi.nlm.nih.gov/pubmed/37940970
http://dx.doi.org/10.1186/s12964-023-01188-z

Ejemplares similares