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Pharmacokinetic–pharmacodynamic cutoff values for benzylpenicillin in horses to support the establishment of clinical breakpoints for benzylpenicillin antimicrobial susceptibility testing in horses

INTRODUCTION: The aim of this international project was to establish a species-specific Clinical Breakpoint for interpretation of Antimicrobial Susceptibility Testing of benzylpenicillin (BP) in horses. METHODS: A population pharmacokinetic model of BP disposition was developed to compute PK/PD cuto...

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Detalles Bibliográficos
Autores principales: Lallemand, Elodie A., Bousquet-Mélou, Alain, Chapuis, Laura, Davis, Jennifer, Ferran, Aude A., Kukanich, Butch, Kuroda, Taisuke, Lacroix, Marlène Z., Minamijima, Yohei, Olsén, Lena, Pelligand, Ludovic, Portugal, Felipe Ramon, Roques, Béatrice B., Santschi, Elizabeth M., Wilson, Katherine E., Toutain, Pierre-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634207/
https://www.ncbi.nlm.nih.gov/pubmed/37954237
http://dx.doi.org/10.3389/fmicb.2023.1282949