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Modular Approach for the Synthesis and Bioactivity Profiling of 8,8′-Biflavones

[Image: see text] In this work, we report the scalable and modular synthesis of a library of 55 monomeric and dimeric flavonoids including 14 8,8′-biflavones. The sterically demanding tetra-ortho-substituted axis of an acetophenone dimer key intermediate was constructed in a regioselective manner us...

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Detalles Bibliográficos
Autores principales: Klischan, Moritz K. T., Mazzone, Flaminia, Berning, Lena, Greb, Julian, Schlamkow, Max, Haase, Mona, Frey, Wolfgang, Stork, Björn, Pfeffer, Klaus, Pietruszka, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634270/
https://www.ncbi.nlm.nih.gov/pubmed/37970025
http://dx.doi.org/10.1021/acsomega.3c06503