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PARK7 Catalyzes Stereospecific Detoxification of Methylglyoxal Consistent with Glyoxalase and Not Deglycase Function

[Image: see text] The protein PARK7 (also known as DJ-1) has been implicated in several diseases, with the most notable being Parkinson’s disease. While several molecular and cellular roles have been ascribed to DJ-1, there is no real consensus on what its true cellular functions are and how the los...

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Detalles Bibliográficos
Autores principales: Coukos, John S., Lee, Chris W., Pillai, Kavya S., Shah, Hardik, Moellering, Raymond E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634309/
https://www.ncbi.nlm.nih.gov/pubmed/37884446
http://dx.doi.org/10.1021/acs.biochem.3c00325