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DNA damage repair mutations in pancreatic cancer– prognostic or predictive?

OBJECTIVE: The efficacy of platinum-based chemotherapy (PtCh) for pancreatic cancer (PC) patients with DNA damage repair gene mutations (DDRm) compared to those without DDRm remains uncertain. METHODS: After a thorough database searching in PubMed, Embase, and Web of Science, a total of 19 studies t...

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Detalles Bibliográficos
Autores principales: Hu, Ya-Fei, Hu, Hai-Jie, Kung, Heng-Chung, Lv, Tian-Run, Yu, Jun, Li, Fu-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634423/
https://www.ncbi.nlm.nih.gov/pubmed/37954082
http://dx.doi.org/10.3389/fonc.2023.1267577