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Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model

Introduction: Dapagliflozin-induced improvement of glycemic control in patients with inadequately controlled type 1 diabetes (T1D) is complicated by the delicate balance between blood glucose and exogenous insulin. In this work, we developed a semi-mechanistic population exposure-response model usin...

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Detalles Bibliográficos
Autores principales: Sokolov, Victor, Yakovleva, Tatiana, Penland, Robert C., Boulton, David W., Tang, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634426/
https://www.ncbi.nlm.nih.gov/pubmed/37954838
http://dx.doi.org/10.3389/fphar.2023.1229255