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Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model
Introduction: Dapagliflozin-induced improvement of glycemic control in patients with inadequately controlled type 1 diabetes (T1D) is complicated by the delicate balance between blood glucose and exogenous insulin. In this work, we developed a semi-mechanistic population exposure-response model usin...
Autores principales: | Sokolov, Victor, Yakovleva, Tatiana, Penland, Robert C., Boulton, David W., Tang, Weifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634426/ https://www.ncbi.nlm.nih.gov/pubmed/37954838 http://dx.doi.org/10.3389/fphar.2023.1229255 |
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