Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice

Emerging evidence suggests that peripheral immune cells contribute to Alzheimer’s disease (AD) neuropathogenesis. Among these, mast cells are known for their functions in allergic reactions and neuroinflammation; however, little is known about their role in AD. Here, we crossed 5XFAD mice with mast...

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Detalles Bibliográficos
Autores principales: Jerry Lin, Chih-Chung, Herisson, Fanny, Le, Hoang, Jaafar, Nader, Chetal, Kashish, Oram, Mary K., Flynn, Kelly L., Gavrilles, Evan P., Sadreyev, Ruslan I., Schiffino, Felipe L., Tanzi, Rudolph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634538/
https://www.ncbi.nlm.nih.gov/pubmed/37713312
http://dx.doi.org/10.1016/j.celrep.2023.113141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634538/
https://www.ncbi.nlm.nih.gov/pubmed/37713312
http://dx.doi.org/10.1016/j.celrep.2023.113141

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