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Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice
Emerging evidence suggests that peripheral immune cells contribute to Alzheimer’s disease (AD) neuropathogenesis. Among these, mast cells are known for their functions in allergic reactions and neuroinflammation; however, little is known about their role in AD. Here, we crossed 5XFAD mice with mast...
Autores principales: | Jerry Lin, Chih-Chung, Herisson, Fanny, Le, Hoang, Jaafar, Nader, Chetal, Kashish, Oram, Mary K., Flynn, Kelly L., Gavrilles, Evan P., Sadreyev, Ruslan I., Schiffino, Felipe L., Tanzi, Rudolph E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634538/ https://www.ncbi.nlm.nih.gov/pubmed/37713312 http://dx.doi.org/10.1016/j.celrep.2023.113141 |
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