Uncoupling the distinct functions of HP1 proteins during heterochromatin establishment and maintenance

H3K9 methylation (H3K9me) marks transcriptionally silent genomic regions called heterochromatin. HP1 proteins are required to establish and maintain heterochromatin. HP1 proteins bind to H3K9me, recruit factors that promote heterochromatin formation, and oligomerize to form phase-separated condensat...

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Detalles Bibliográficos
Autores principales: Seman, Melissa, Levashkevich, Alexander, Larkin, Ajay, Huang, Fengting, Ragunathan, Kaushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634687/
https://www.ncbi.nlm.nih.gov/pubmed/37961629
http://dx.doi.org/10.1101/2023.04.30.538869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634687/
https://www.ncbi.nlm.nih.gov/pubmed/37961629
http://dx.doi.org/10.1101/2023.04.30.538869

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