Cellular rules underlying psychedelic control of prefrontal pyramidal neurons

Classical psychedelic drugs are thought to increase excitability of pyramidal cells in prefrontal cortex via activation of serotonin 2(A) receptors (5-HT2(A)Rs). Here, we instead find that multiple classes of psychedelics dose-dependently suppress intrinsic excitability of pyramidal neurons, and tha...

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Detalles Bibliográficos
Autores principales: Ekins, Tyler G, Brooks, Isla, Kailasa, Sameer, Rybicki-Kler, Chloe, Jedrasiak-Cape, Izabela, Donoho, Ethan, Mashour, George A., Rech, Jason, Ahmed, Omar J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634703/
https://www.ncbi.nlm.nih.gov/pubmed/37961554
http://dx.doi.org/10.1101/2023.10.20.563334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634703/
https://www.ncbi.nlm.nih.gov/pubmed/37961554
http://dx.doi.org/10.1101/2023.10.20.563334

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