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Design of intrinsically disordered protein variants with diverse structural properties

Intrinsically disordered proteins (IDPs) perform a wide range of functions in biology, suggesting that the ability to design IDPs could help expand the repertoire of proteins with novel functions. Designing IDPs with specific structural or functional properties has, however, been difficult, in part...

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Detalles Bibliográficos
Autores principales: Pesce, Francesco, Bremer, Anne, Tesei, Giulio, Hopkins, Jesse B., Grace, Christy R., Mittag, Tanja, Lindorff-Larsen, Kresten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634714/
https://www.ncbi.nlm.nih.gov/pubmed/37961110
http://dx.doi.org/10.1101/2023.10.22.563461